Research
We are adopting non-invasive approaches that:
- control drug release kinetics through stimuli-responsive [1,2,3,4, 5] or biodegradable systems [6,7,8],
- enhance drug solubility in body fluids [9,10,11,12,13] and/or drug absorption across mucosal surfaces [13,14,15,16,17],
- prolong drug retention at the site of action [18,19,20,21,22] and
- facilitate improved patient adherence by developing easy-to-administer dosage forms for sensitive patient groups (pediatric, geriatric) [23,24,25,26] and devising drug consolidation approaches.[27,28]
Our research includes extensive use of ex vivo tissue models (animal/human) to better simulate the biological environment and predict the in vivo performance of the developed drug delivery systems and devices. We are also interested in knowledge-sourcing from nature-inspired materials and processes for a wide range of biomedical applications.